Injury from blast overpressure is unique to blast events but not well understood, particularly in the area of mild traumatic brain injury (mTBI). To address this knowledge gap, the Department of Defense (DoD) Blast Injury Research Coordinating Office (BIRCO), in coordination with the Defense Centers of Excellence for Psychological Health and Traumatic Brain Injury (DCoE), hosted the International State-of-the-Science (SoS) Meeting on Non-Impact, Blast-Induced Mild Traumatic Brain Injury on May 12–14, 2009, in Herndon, Virginia. This inaugural SoS meeting explored the significant and outstanding question of whether blast overpressure alone can cause mTBI, and if so, what are the injury mechanisms. Understanding the mechanism of any injury is key to developing effective prevention, treatment, and rehabilitation strategies.
The purpose and objective of this meeting was to critically examine research focused on the relationship between blast exposure and non-impact, blast-induced mTBI and to review proposed injury mechanisms.
The meeting participants were charged with answering the following questions during the working group sessions:
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